Journal of Applied Biosciences (J. Appl. Biosci.) [ISSN 1997 - 5902]
Volume 51: 3618 - 3624. Published March 29, 2012.
Effect of Crude oil contaminated water on the guinea pig (Cavia porcellus): Ileum morphological cum histological perspectives.
1Mbadugha C. Christopher , 1Aquaisua N. Aquaisua, 1Eno-obong I. Bassey,1Aniekan I. Peter, 1Edagha A. Innocent, 2Bankole J. Leko.
1 Department of Anatomy, Faculty of Basic Medical Sciences, University of Uyo,P.M.B.1017, Uyo, Akwa Ibom State, Nigeria.
2 Department of Anatomy, Faculty of Basic Medical Sciences, Madonna University, Elele, Rivers State, Nigeria.
RESUME
Objective: is to determine the harmful effects of crude oil contaminated water on the guinea pig and the histology of its ileum.
Methodology and result: Twenty four guinea pigs were divided into four groups, comprising of control group A, and experimental groups: B, C, and D. They were allowed to acclimatize for two weeks, and were fed elephant grass and tap water. With insulin syringe, 1 mil (approximately equivalent to 10 drops) of crude oil contaminated water was administered to the experimental groups: B,C, and D; once, twice, and thrice, daily, respectively, for six weeks. It was observed that the histological architecture of group A, were intact, while that of the experimental groups were disrupted, the degree of disruption was directly proportional to the concentration of crude oil contaminated water administered.
Conclusion and application of findings: Ingestion of crude oil contaminated water is detrimental to health. The findings from this study may be useful in making valid and informed decisions for public consumption, as regards the health implication of eating and drinking crude oil contaminated food and water respectively.
Key words: Crude oil contaminated water, Guinea pig, Tap water.
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