This study was carried out to evaluate the effect of high dietary energy as calcium salt dry fat and protected methionine on serum and tissues magnesium (Mg), copper (Cu), zinc (Zn), iron (Fe) and cobalt (Co) concentrations of Awassi lambs during finishing stage. Twenty-four Awassi lambs (3 to 4 month old) were distributed equally to four treatments groups as follow: Control (Regular ration; NRC requirements); T1 (High energy 3.0 Mcal ME/ kg); T2 (high energy 3.0 Mcal ME/ kg and 2.5 methionine/ head/ day as Smartamine) and T3 (high energy 3.0 Mcal ME/ kg and 5g/ head/ day methionine as Smartamine). A significant effect of treatment on livers' cobalt, copper and iron were found with variable change between each mineral and groups. Zinc and Mg concentration in blood serum showed significantly lower values for the final blood sampling compared with the initial in all groups with a significantly (P<0.05) lower Zn and higher Mg values for the control compared with other groups. Otherwise, treatment didn't cause any effect on Cu and Co concentrations in the blood serum.  In conclusion, increasing dietary energy by using calcium salt dry fat up to 3% with protected methionine up to 5g/day for growing Awassi lambs during the finishing period can be used without any negative effect on their minerals bioavailability and consequently their health and performance.